Effects of leptin and MT-II on glucose uptake Distinct effects of leptin and a melanocortin receptor agonist injected into medial hypothalamic nuclei on glucose uptake in peripheral tissues Short running title: Effects of leptin and MT-II on glucose uptake
نویسندگان
چکیده
Chitoku Toda, Tetsuya Shiuchi, Suni Lee, Maya Yamato-Esaki, Yusuke Fujino, Atsushi Suzuki, Shiki Okamoto, Yasuhiko Minokoshi* Department of Physiological Sciences, Graduate University for Advanced Studies (Sokendai), Hayama, Kanagawa 240-0193, Japan Division of Endocrinology and Metabolism, Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan Department of Internal Medicine 1, Faculty of Medicine, Oita University, Hasama, Oita 879-5593, Japan
منابع مشابه
Distinct Effects of Leptin and a Melanocortin Receptor Agonist Injected Into Medial Hypothalamic Nuclei on Glucose Uptake in Peripheral Tissues
OBJECTIVE The medial hypothalamus mediates leptin-induced glucose uptake in peripheral tissues, and brain melanocortin receptors (MCRs) mediate certain central effects of leptin. However, the contributions of the leptin receptor and MCRs in individual medial hypothalamic nuclei to regulation of peripheral glucose uptake have remained unclear. We examined the effects of an injection of leptin an...
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